MAO

«Monoamine oxidases (MAO) (EC1.4.3.4) are a family of enzymes that catalyze the oxidation of monoamines, employing oxygen to clip off their amine group.[1][2] They are found bound to the outer membrane of mitochondria in most cell types of the body. The first such enzyme was discovered in 1928 by Mary Bernheim in the liver and was name tyramine oxidase.[3][4] The MAO belong to the protein family of flavin-containing amine oxidoreductases.

MAO are important in the breakdown of monoamines ingested in food, and also serve to inactivate monoamine neurotransmitters. Because of the latter, they are involved in a number of psychiatric and neurological diseases, some of which can be treated with monoamine oxidase inhibitors (MAOIs) which block the action of MAO(wikipedia)

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Pathways of MAO

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Insider BiohackerPRO ranked added it 1 year ago on Dec 20, 2018