Hydrogen-rich water for improvements of mood, anxiety, and autonomic nerve function in daily life
These results suggest that HRW may be effective for reducing accumulated oxidative stress in the brain in daily life, potentially contributing to the maintenance of central nervous system activity and preventing decreases in QOL.
Effects of the long-term consumption of hydrogen-rich water on the antioxidant activity and the gut flora in female juvenile soccer players from Suzhou, China
After 4 weeks, the level of serum IL-6decreased from 19.48 ± 2.16 to 10.53 ± 1.62 ng/L in the control group and from 17.72 ± 2.1 to 8.74 ± 2.57 ng/L in the hydrogen-rich water treatment group. After 8 weeks, the level of serum IL-6 in the control group increased from 10.53 ± 1.62 ng/L to 24.88 ± 6.11 ng/L, while that in the hydrogen-rich water treatment group increased from 8.74 ± 2.57 to 12.37 ± 3.2 ng/L, with significant differences between the two groups (P = 0.000, Figure 4B).
Administration of hydrogen-rich water prevents vascular aging of the aorta in LDL receptor-deficient mice.
«The main cause of arteriosclerosis is atherosclerosis in the aorta. Atherosclerosis is recognized as a chronic inflammatory condition that begins with the dysfunction or activation of arterial endothelium. Low-density lipoprotein (LDL) and especially its oxidized form play a key role in endothelial dysfunction and atherogenesis. Recent studies showed that senescent cellsare involved in the development and progression of atherosclerosis, and eliminating senescent cellssuppresses the senescence-associated secretory phenotype. We previously reported that molecular hydrogen-rich water (HW) has antioxidant and anti-inflammatory effects in numerous diseases. Here, we used LDL receptor-deficient mice fed a high-fat diet (HFD) for 13 weeks as a model for atherosclerosis and evaluated the effects of continuous administration of HW. The numbers of endothelial cells in the atheroma expressing the senescence factors p16INK4a and p21 decreased in HFD-fed mice given HW compared with HFD-fed mice given control water. Furthermore, macrophage infiltration and Tnfα expression in the atheroma were also suppressed. These results suggest that vascular aging can be suppressed by HW.»