Interleukin-12
IL-12
cytokine
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«Interleukin 12 (IL-12) is an interleukin that is naturally produced by dendritic cell,[1]macrophage, neutrophil, and human B-lymphoblastoid cell (NC-37) in response to antigenic stimulation.» (wikipedia)
Summary on IL-12
Interleukin-12 is
a
cytokine.
Here is an overview of its
14 biolinks
with
acceptable
average validity.
Bolder font means better proofs.
Alt+click opens node.
It is:
Anti-inflammatory cytokines
IL-12S:
IL-12p70
→ Increased by:
AGEs
→ May be increased by:
Beta-glucans, LDN
↘ May be decreased by:
Ghrelin
? Affects:
Psoriasis
? Affected by:
Hashimoto Thyroiditis, Psoriasis
× Is not affected by:
Endometriosis
Pathways of IL-12
Textual paths of Biolinks with
Validity Score > 3.0
This tool shows paths like:
A B C IL-12
Evidence Sources
Biolinks for IL-12 are extracted by users from 15 related publications.
Users read a research at the PubMed. They understand a relation between two objects.
To organise this new finding, they add it as a new piece of information — a Biolink — a proven logical relation between objects, drugs or symptoms etc.
Any user can propose new knowledge which will be reviewed.
Proofs for biolinks of current node (IL-12) are listed here. Abstracts are hidden.
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2000Publications Review
- Organism: Humans
- Notable Magnitude of Effect.
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2003Cohort
- Organism: Humans
- Notable Magnitude of Effect.
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2007Publications Review
- Organism: Humans
- Notable Magnitude of Effect.
-
-
2009
-
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2016Rodents
- Organism: Mouse / Rat (Rodents)
- Notable Magnitude of Effect.
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2018Rodents
- Organism: Mouse / Rat (Rodents)
- Notable Magnitude of Effect.
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-
2020Human Cells
- Organism: In vitro
- Notable Magnitude of Effect.
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2020Publications Review
- Organism: Humans
- Notable Magnitude of Effect.
-
-
2021Publications Review
- Organism: Humans
- Notable Magnitude of Effect.
-
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1996Publications Review
- Organism: Humans
- Notable Magnitude of Effect.
-
-
2011
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2015Cohort
- Organism: Humans
- Notable Magnitude of Effect.
-
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2005Cohort
- Organism: Humans
- Notable Magnitude of Effect.
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-
2006
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2017Human Cells
- Organism: In vitro
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See extended map
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Map IL-12 to ...
NB! This is beta feature, which sometimes hangs. We are working on optimising it.
Do something with IL-12
Lists what BioMindmap can do with its medical objects for demo purposes.
Biolink is a statement and objects connection.
- See 14 Biolinks that connect IL-12 with other objects
- Group Biolinks by type — promoters and inhibitors separately
- Summarize how other objects relate to IL-12
Biolinks should be proven by researches.
- There are 15 Evidences supporting 14 IL-12 Biolinks
- See
Guide for Good Sources list of respected domains.
The ValidityScore shows the quality of evidences, with max 9.9.
Textual Paths like
A
→
B
→
C
→
IL-12. can be generated from biolinks.
Visualise biolinks!
- IL-12 Mindmap — near connections
- Mindmap with ValidityScore 5.0 — near connections
- Mindmap of IL-12. and Subnodes: .
- Find Path to another object.
- Build Custom Map
IL-12 has 10 incoming and 4 outgoing biolinks:
- Instream into nodes that connect into IL-12.
- Outstream from nodes that go out from IL-12.
- Promoters of IL-12
When you read PubMed research organise your findings here.
- Add biolink i.e. «X increases IL-12». Intuitively easy.
Become better
- Power-start: watch the Intro Video and Guide in Help Center
- Users improve Reputation by getting experienced and validated.
Other options
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