NAC • How it works? Researched 33 times | BioMindmap.com

N-Acetylcysteine NAC metabolite

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«Acetylcysteine, also known as N-acetylcysteine (NAC), is a medication that is used to treat paracetamol (acetaminophen) overdose, and to loosen thick mucus in individuals with cystic fibrosis or chronic obstructive pulmonary disease.^[1] It can be taken intravenously, by mouth, or inhaled as a mist.^[1] Some people use it as a dietary supplement.^[6]^[7]

N-Acetylcysteine is a metabolite. Here is an overview of its with

Classification

Bolder font means better proofs. Alt+click opens node.

It is:

Biochemistry of NAC

↑ Increases: ,

↑ May increase: , , ,

↓ Decreases: , , ,

↓ May decrease: , , , , ,

Effects

↑ Improves or cures: , , , , , ,

↑ May improve: , ,

↓ May worsen:

Sources

→ Increased by: ,

→ May be increased with an increase of cofactors:

Correlation

? Affected by:

Absence of Correlation

× Does not affect:

Pathways of NAC

Textual paths of Biolinks with Validity Score > 3.0

How to increase NAC?

How to decrease NAC?

What NAC increases or causes?

What NAC decreases?

Paths that connect NAC with other objects (coming soon)?

Uses in-app credits

This tool shows paths like: A B C NAC

Mindmaps

Visualisation of logical biolinks between drugs, supplements, symptoms etc..

NAC Biolinks

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Obviously Glycine + NAC contains NAC
—
Obviously NAC + ALA + Bromelain contains NAC
5.3
NAC prevents TNF-α
5.3
NAC prevents IL-6
5.3
NAC prevents IL-1β
5.3
NAC prevents IL-8
5.2
NAC improves Cognition
5.0
NAC does reduce Stay in ICU
5.0
NAC prevents All-Cause Mortality
4.9
NAC does not affect Helicobacter pylori
4.8
NAC prevents Atrial fibrillation
4.6
NAC may attenuate Schizophrenia
4.3
NAC may cure Acne
2.4
NAC increases Tumorigenesis
(BioMindmap Proof Quality is Low.)
2.4
NAC decreases Cancer Survival
(BioMindmap Proof Quality is Low.)
2.4
NAC inactivates P53
(BioMindmap Proof Quality is Low.)
2.3
Glutathione precursors NAC
(BioMindmap Proof Quality is Low.)
2.3
NAC inhibits NF-kB
(BioMindmap Proof Quality is Low.)
2.1
NAC increases Tumorigenesis
(BioMindmap Proof Quality is Low.)
1.8
NAC lowers Oxidative stress
(BioMindmap Proof Quality is Low.)
1.8
NAC counteracts Aldosterone
(BioMindmap Proof Quality is Low.)
1.7
NAC inhibits Akt
(BioMindmap Proof Quality is Low.)
1.7
NAC inhibits MAPK
(BioMindmap Proof Quality is Low.)
1.5
NAC inhibits Biofilm
(BioMindmap Proof Quality is Low.)
0.7
NAC may increase Telomerase
(BioMindmap Proof Quality is Very Light.)
0.7
NAC may increase SIRT2
(BioMindmap Proof Quality is Very Light.)
0.7
NAC may increase SIRT1
(BioMindmap Proof Quality is Very Light.)
0.7
NAC may decrease Oocyte aging
(BioMindmap Proof Quality is Very Light.)
0.5
Perhaps, NAC is Antioxidant
(Not proven by a research!)
0.4
NAC may cure Beta-cells
(BioMindmap Proof Quality is Very Light.)
-1.1
Perhaps, Vitamin B12 dangerously interacts with NAC
(BioMindmap Proof Quality is Negative.)
-1.4
Perhaps, NAC increases Brain Blood Flow
(BioMindmap Proof Quality is Negative.)
-2.2
Perhaps, NAC may worsen Tumorigenesis
(BioMindmap Proof Quality is Negative.)

Evidence Sources

Biolinks for NAC are extracted by users from 14 related publications.

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