«A biofilm comprises any syntrophic consortium of microorganisms in which cell stick to each other and often also to a surface. These adherent cell become embedded within a slimy extracellular matrix that is composed of extracellular polymeric substances (EPS). The cell within the biofilm produce the EPS components, which are typically a polymeric conglomeration of extracellular polysaccharides, proteins, lipids and DNA. Because they have three-dimensional structure and represent a community lifestyle for microorganisms, they have been metaphorically described as "cities for microbes".
Biofilms may form on living or non-living surfaces and can be prevalent in natural, industrial and hospital settings. The microbial cell growing in a biofilm are physiologically distinct from planktonic cell of the same organism, which, by contrast, are single-cell that may float or swim in a liquid medium. Biofilms can form on the teeth of most animals as dental plaque, where they may cause tooth decay and gum disease.
Microbes form a biofilm in response to various different factors, which may include cellular recognition of specific or non-specific attachment sites on a surface, nutritional cues, or in some cases, by exposure of planktonic cell to sub-inhibitory concentration of antibiotics. A cell that switches to the biofilm mode of growth undergoes a phenotypic shift in behavior in which large suites of genes are differentially regulated.
A biofilm may also be considered a hydrogel, which is a complex polymer that contains many times its dry weight in water. Biofilms are not just bacterial slime layers but biological systems; the bacteria organize themselves into a coordinated functional community. Biofilms can attach to a surface such as a tooth, rock, or surface, and may include a single species or a diverse group of microorganisms. The biofilm bacteria can share nutrients and are sheltered from harmful factors in the environment, such as desiccation, antibiotics, and a host body's immune system. A biofilm usually begins to form when a free-swimming bacterium attaches to a surface.[page needed]» (wikipedia)
Do something with Biofilm, already
This screen hints what BioMindmap can do with medical objects
- See 5 Biolinks that connect Biofilm with other objects
- Group Biolinks by type — promoters and inhibitors separately
- Summarize how other objects relate to Biofilm
- There are 5 Evidences supporting 5 Biofilm Biolinks
Guide for Good Sources list of respected domains.
The ValidityScore showsthe quality of evidences, with max 9.9.
- Biofilm Mindmap — near connections
- Mindmap with ValidityScore 5.0 — near connections
- Mindmap of Biofilm. and Subnodes: .
- Find Path to another object.
- Build Custom Map
- Add biolink i.e. «X increases Biofilm». Intuitively easy.
- Power-start: watch the Intro Video and Guide in Help Center
- Users improve Reputation by getting experienced and validated.
- Ask Telegram Bot to get quick Summary on any object.