«FOX (Forkhead box) proteins are a family of transcription factors that play important roles in regulating the expression of genes involved in cell growth, proliferation, differentiation, and longevity. Many FOX proteins are important to embryonic development.[1][2] FOX proteins also have pioneering transcription activity by being able to bind condensed chromatin during cell differentiation processes.[3]

The defining feature of FOX proteins is the forkhead box, a sequence of 80 to 100 amino acids forming a motif that binds to DNA. This forkhead motif is also known as the winged helix due to the butterfly-like appearance of the loops in the protein structure of the domain.[4] Forkhead proteins are a subgroup of the helix-turn-helix class of proteins.» (wikipedia)

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Modified: 8 months ago on Dec 30, 2018
personAlex Inside 23 lvl added it 1 year ago on Jul 26, 2018.