Polyunsaturated Fatty Acid
PUFA
fatty acid
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«Polyunsaturated fatty acid (PUFAs) are fatty acids that contain more than one double bond in their backbone. This class includes many important compounds, such as essential fatty acids and those that give drying oils their characteristic property.
Polyunsaturated fatty acid can be classified in various groups by their chemical structure:» (wikipedia)
Summary on PUFA
Polyunsaturated Fatty Acid is
a
fatty acid.
Here is an overview of its
25 biolinks
with
acceptable
average validity.
Bolder font means better proofs.
Alt+click opens node.
PUFAS:
Arachidonic acid
Biochemistry of PUFA
↑ May increase:
Insulin sensitivity
↓ Decreases:
CRP, Disease activity, IL-6, Joint symptoms, Leptin, Lifespan, Morning stiffness, NF-kB, Pain, TNF-α
↓ May decrease:
Ischemic Heart Disease
↑ Improves or cures:
Neurogenesis
↑ May improve:
Blood pressure, Ischemic Heart Disease
→ Increased by:
Pufa + Breastfeeding
↘ Decreased by:
Depression
? Affects:
NSAID
Pathways of PUFA
Textual paths of Biolinks with
Validity Score > 3.0
This tool shows paths like:
A B C PUFA
Evidence Sources
Biolinks for PUFA are extracted by users from 14 related publications.
Users read a research at the PubMed. They understand a relation between two objects.
To organise this new finding, they add it as a new piece of information — a Biolink — a proven logical relation between objects, drugs or symptoms etc.
Any user can propose new knowledge which will be reviewed.
Proofs for biolinks of current node (PUFA) are listed here. Abstracts are hidden.
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2005Cohort
- Organism: Females
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2005Cohort
- Organism: Females
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2011Rodents
- Organism: Mouse / Rat (Rodents)
- Notable Magnitude of Effect.
-
-
2014Meta-Analysis
- Organism: Humans
- Strong Magnitude of Effect.
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2014Meta-Analysis
- Organism: Humans
- Strong Magnitude of Effect.
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2014Rodents
- Organism: Mouse / Rat (Rodents)
- Notable Magnitude of Effect.
-
-
2015Rodents
- Condition: Calorie restriction (CR)
- Organism: Mouse / Rat (Rodents)
- Notable Magnitude of Effect.
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-
2014Systematic Review
- Organism: Humans
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-
2015
-
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2017Publications Review
- Organism: Humans
- Strong Magnitude of Effect.
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-
2018
-
-
2018
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-
2018
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-
2012Publications Review
- Organism: Humans
- Minor Magnitude of Effect.
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See extended map
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Map PUFA to ...
NB! This is beta feature, which sometimes hangs. We are working on optimising it.
Do something with PUFA
Lists what BioMindmap can do with its medical objects for demo purposes.
Biolink is a statement and objects connection.
- See 25 Biolinks that connect PUFA with other objects
- Group Biolinks by type — promoters and inhibitors separately
- Summarize how other objects relate to PUFA
Biolinks should be proven by researches.
- There are 14 Evidences supporting 25 PUFA Biolinks
- See
Guide for Good Sources list of respected domains.
The ValidityScore shows the quality of evidences, with max 9.9.
Textual Paths like
A
→
B
→
C
→
PUFA. can be generated from biolinks.
Visualise biolinks!
- PUFA Mindmap — near connections
- Mindmap with ValidityScore 5.0 — near connections
- Mindmap of PUFA. and Subnodes: .
- Find Path to another object.
- Build Custom Map
PUFA has 3 incoming and 22 outgoing biolinks:
- Instream into nodes that connect into PUFA.
- Outstream from nodes that go out from PUFA.
- Promoters of PUFA
When you read PubMed research organise your findings here.
- Add biolink i.e. «X increases PUFA». Intuitively easy.
Become better
- Power-start: watch the Intro Video and Guide in Help Center
- Users improve Reputation by getting experienced and validated.
Other options
- Ask Telegram Bot to get quick Summary on any object.
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