C-Reactive Protein CRP marker

«C-reactive protein (CRP) is an annular (ring-shaped), pentameric protein found in blood plasma, whose circulating concentration rise in response to inflammation. It is an acute-phase protein of hepatic origin that increases following interleukin-6 secretion by macrophages and T cell. Its physiological role is to bind to lysophosphatidylcholine expressed on the surface of dead or dying cell (and some types of bacteria) in order to activate the complement system via C1q.[5]

CRP is synthesized by the liver[6] in response to factors released by macrophages and fat cell (adipocytes).[7] It is a member of the pentraxin family of proteins.[6] It is not related to C-peptide (insulin) or protein C (blood coagulation). C-reactive protein was the first pattern recognition receptor (PRR) to be identified.» (wikipedia)

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Pathways of CRP

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