C-Reactive Protein
CRP
marker
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«C-reactive protein (CRP) is an annular (ring-shaped), pentameric protein found in blood plasma, whose circulating concentration rise in response to inflammation. It is an acute-phase protein of hepatic origin that increases following interleukin-6 secretion by macrophage and T cell. Its physiological role is to bind to lysophosphatidylcholine expressed on the surface of dead or dying cell (and some types of bacteria) in order to activate the complement system via C1q.[5]
CRP is synthesized by the liver[6] in response to factors released by macrophage and fat cell (adipocytes).[7] It is a member of the pentraxin family of proteins.[6] It is not related to C-peptide (insulin) or protein C (blood coagulation). C-reactive protein was the first pattern recognition receptor (PRR) to be identified.» (wikipedia)
Summary on CRP
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Lowering of CRP
Pathways of CRP
Evidence Sources
Biolinks for CRP are extracted by users from 44 related publications.-
2011RCT
- Organism: Humans
- Notable Magnitude of Effect.
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2011RCT
- Organism: Humans
- Minor Magnitude of Effect.
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2012RCT
- Organism: Humans
- Minor Magnitude of Effect.
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2015RCT
- Organism: Humans
- Minor Magnitude of Effect.
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2018RCT
- Organism: Humans
- Minor Magnitude of Effect.
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2019RCT
- Organism: Humans
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2004RCT
- Organism: Humans
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2014Meta-Analysis
- Organism: Humans
- Strong Magnitude of Effect.
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2017Cohort
- Organism: Humans
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2018RCT
- Condition: in older men with low testosterone
- Organism: Humans
- Minor Magnitude of Effect.
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2019Meta-Analysis
- Organism: Humans
- Notable Magnitude of Effect.
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2019Meta-Analysis
- Condition: in patients with diabetes and CVD
- Organism: Humans — Not Healthy
- Notable Magnitude of Effect.
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2019Systematic Review
- Organism: Humans
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2020RCT
- Organism: Females
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2020RCT
- Organism: Humans — Old
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2015RCT
- Organism: Humans
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2015
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2015Systematic Review
- Organism: Humans
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2016
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2016Systematic Review
- Organism: Humans
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2017RCT
- Organism: Humans — Not Healthy
- Notable Magnitude of Effect.
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2006RCT
- Dose: 1500 mg
- Condition: Metabolic syndrome
- Organism: Humans
- Notable Magnitude of Effect.
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2009
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2010
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2012Meta-Analysis
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2013
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2013
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2015
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2016Systematic Review
- Organism: Humans — Not Healthy
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2017
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2017
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2017
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2017Meta-Analysis
- Organism: Humans
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2017RCT
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2017
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2018Meta-Analysis
- Organism: Humans
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2018
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2019Systematic Review
- Organism: Humans
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2019Systematic Review
- Organism: Humans
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2019RCT
- Organism: Humans
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2020RCT
- Organism: Humans
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2020RCT
- Dose: 2.4g
- Condition: patients with chronic kidney disease in hemodialysis
- Organism: Humans
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- Organism: Humans
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- See 36 Biolinks that connect CRP with other objects
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- Summarize how other objects relate to CRP
- There are 44 Evidences supporting 36 CRP Biolinks
- See
Guide for Good Sources list of respected domains.
The ValidityScore shows the quality of evidences, with max 9.9.
- CRP Mindmap — near connections
- Mindmap with ValidityScore 5.0 — near connections
- Mindmap of CRP. and Subnodes: .
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- Promoters of CRP
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