Glycated Hemoglobin A1C
HbA1C
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Marker of glucose exposure onto proteins within a blood sample.
«It is important to note that the HbA1c levels are directly proportional to the blood glucose levels.»
«There is a direct correlation between HbA1c and insulin resistance, where HbA1c has been shown to be more strongly associated with the insulin sensitivity in healthy subjects with normal glucose tolerance.»
«Glycated hemoglobin (hemoglobin A1c, HbA1c, A1C, or less commonly HgbA1c, haemoglobin A1c, HbA1c, Hb1c, etc.) is a form of hemoglobin that is bound to glucose. It is formed in a non-enzymatic glycation pathway by hemoglobin's exposure to plasma glucose. It is measured primarily to identify the three-month average plasma glucose concentration and thus can be used as a diagnostic test for diabetes and as assessment test for glycemic control in people with diabetes[1]. The test is limited to a three-month average because the lifespan of a red blood cell is four months (120 days).» (wikipedia)
Summary on HbA1C
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Lowering of HbA1C
Pathways of HbA1C
Evidence Sources
Biolinks for HbA1C are extracted by users from 24 related publications.-
2019RCT
- Organism: Humans
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2008
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2013Meta-Analysis
- Organism: Humans
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2015Meta-Analysis
- Condition: in (pre-)diabetic patients
- Organism: Humans — Not Healthy
- Minor Magnitude of Effect.
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2018RCT
- Condition: in older men with low testosterone
- Organism: Humans
- Minor Magnitude of Effect.
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2019Meta-Analysis
- Condition: in patients with T2DM
- Organism: Humans — Not Healthy
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2019Meta-Analysis
- Organism: Humans
- Minor Magnitude of Effect.
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2014Non Random CT
- Organism: Humans — Not Healthy
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2014
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2016
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2016Systematic Review
- Organism: Humans
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2017
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2017
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2011Cohort
- Organism: Humans
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2012Systematic Review
- Condition: type-2 diabetes
- Organism: Humans
- Notable Magnitude of Effect.
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2014Meta-Analysis
- Organism: Humans
- Strong Magnitude of Effect.
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2017RCT
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2017
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2019RCT
- Condition: patients with type 2 diabetes
- Organism: Humans
- Notable Magnitude of Effect.
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2019RCT
- Condition: women with type 2 diabetes mellitus
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2020RCT
- Condition: Diabetes
- Organism: Humans
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2020RCT
- Dose: 100 mcg
- Organism: Females
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2019Systematic Review
- Condition: type 2 diabetic patients
- Organism: Humans — Not Healthy
- Notable Magnitude of Effect.
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2019
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This screen hints what BioMindmap can do with medical objects
- See 24 Biolinks that connect HbA1C with other objects
- Group Biolinks by type — promoters and inhibitors separately
- Summarize how other objects relate to HbA1C
- There are 24 Evidences supporting 24 HbA1C Biolinks
- See
Guide for Good Sources list of respected domains.
The ValidityScore shows the quality of evidences, with max 9.9.
- HbA1C Mindmap — near connections
- Mindmap with ValidityScore 5.0 — near connections
- Mindmap of HbA1C. and Subnodes: .
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- Instream into nodes that connect into HbA1C.
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- Promoters of HbA1C
- Add biolink i.e. «X increases HbA1C». Intuitively easy.
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