Selective Serotonin Reuptake Inhibitor SSRI drug
« Selective serotonin reuptake inhibitor (SSRI) are a class of drugs that are typically used as antidepressant in the treatment of major depressive disorder and anxiety disorders.
The exact mechanism of action of SSRI is unknown. SSRI are believed to increase the extracellular level of the neurotransmitterserotonin by limiting its reabsorption (reuptake) into the presynaptic cell, increasing the level of serotonin in the synaptic cleft available to bind to the postsynaptic receptor. They have varying degrees of selectivity for the other monoamine transporters, with pure SSRI having only weak affinity for the norepinephrine and dopamine transporters.