Melatonin hormone editEdit

«Melatonin is a hormone, produced by the pineal gland among other locations, which regulates wakefulness.[4] As a medicine, it is used to treat insomnia; however, evidence of benefit is unclear.[5] One review found onset of sleep occurred 6 minutes faster with use but found no change in total time asleep.[6]

Side effects from supplements are minimal at low doses.[3] In animals, melatonin is involved in the entrainment (synchronization) of the circadian rhythm including sleep-wake timing, blood pressure regulation, seasonal reproduction.[7] Many of its biological effects are produced through activation of melatonin receptors,[8] while others are due to its role as an antioxidant,[9] particularly in the protection of nuclear and mitochondrial DNA.[10] In plants it functions as a first line of defense against oxidative stress.[11]

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Modified: 8 months ago on Dec 30, 2018
personAlex Inside 23 lvl added it 1 year ago on Jul 13, 2018.