CXCL12

«The stromal cell-derived factor 1 (SDF1), also known as C-X-C motif chemokine 12 (CXCL12), is a chemokineprotein that in humans is encoded by the CXCL12gene on chromosome 10.[5] It is ubiquitously expressed in many tissues and cell types.[6] Stromal cell-derived factors 1-alpha and 1-beta are small cytokines that belong to the chemokine family, members of which activate leukocytes and are often induced by proinflammatory stimuli such as lipopolysaccharide, TNF, or IL1. The chemokines are characterized by the presence of 4 conserved cysteine that form 2 disulfide bonds. They can be classified into 2 subfamilies. In the CC subfamily, the cysteine residues are adjacent to each other. In the CXC subfamily, they are separated by an intervening amino acid. The SDF1 proteins belong to the latter group.[5] CXCL12 signaling has been observed in several cancer.[7][8] The CXCL12 gene also contains one of 27 SNPs associated with increased risk of coronary artery disease.[9]» (wikipedia)

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Pathways of CXCL12

Textual paths of Biolinks with Validity Score > 3.0
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Visualisation of logical biolinks between drugs, supplements, symptoms etc..
Pavel Solodkin ranked added it 5 months ago on May 11, 2021