Proinflammatory cytokines cytokine
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«An inflammatory cytokine or proinflammatory cytokine is a type of signaling molecule (a cytokine) that is secreted from immune cell like helper T cell (Th) and macrophages, and certain other cell types that promote inflammation. They include interleukin-1 (IL-1), IL-12, and IL-18, tumor necrosis factor alpha (TNF-α), interferon gamma (IFNγ), and granulocyte-macrophage colony stimulating factor (GM-CSF) and play an important role in mediating the innate immune response. Inflammatory cytokines are predominantly produced by and involved in the upregulation of inflammatory reactions.» (wikipedia)

Summary on Proinflammatory cytokines

It is also known as inflammatory cytokine and it is a cytokine. Here is an overview of its 16 biolinks with acceptable average validity.
Proinflammatory cytokines: IFN-α, IFN-β, IFN-γ, IL-1, IL-11, IL-17, IL-18, IL-1β, IL-6, IL-8, TNF-α, TNF-β
↑ Increases: Nitric Oxide
↓ Decreases: BH4, Neurotransmitters
→ Increased by: Major depressive disorder

Pathways of Proinflammatory cytokines

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Evidence Sources

Biolinks for Proinflammatory cytokines are extracted by users from 1 related publications.
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