IFN-γ • How it works? Researched 31 times | BioMindmap.com

Interferon Gamma IFN-γ cytokine

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«Interferon gamma (IFNγ) is a dimerized soluble cytokine that is the only member of the type II class of interferon.^[1] The existence of this interferon, which early in its history was known as immune interferon, was described by E. F. Wheelock as a product of human leukocytes stimulated with phytohemagglutinin, and by others as a product of antigen-stimulated lymphocytes.^[2] It was also shown to be produced in human lymphocytes.^[3] or tuberculin-sensitized mouse peritoneal lymphocytes^[4] challenged with PPD; the resulting supernatants were shown to inhibit growth of vesicular stomatitis virus. Those reports also contained the basic observation underlying the now widely employed interferon gamma release assay used to test for tuberculosis. In humans, the IFNγ protein is encoded by the IFNGgene.^[5]^[6]» (wikipedia)

Interferon Gamma is a cytokine. Here is an overview of its with

Classification

Bolder font means better proofs. Alt+click opens node.

It is: ,

Biochemistry

↑ Increases:

↓ Decreases: ,

Sources

→ Increased by: , , , ,

Lowering of IFN-γ

↘ Decreased by: , , , , , , , , , , , ,

↘ May be decreased by: , , ,

Correlation

? Affects:

? Affected by: , ,

Pathways of IFN-γ

Textual paths of Biolinks with Validity Score > 3.0

How to increase IFN-γ?

How to decrease IFN-γ?

What IFN-γ increases or causes?

What IFN-γ decreases?

Paths that connect IFN-γ with other objects (coming soon)?

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This tool shows paths like: A B C IFN-γ

Mindmaps

Visualisation of logical biolinks between drugs, supplements, symptoms etc..

IFN-γ Biolinks

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Obviously IFN-γ is Proinflammatory cytokine
6.9
Th1 produces IFN-γ
5.5
Depression decreases IFN-γ
5.3
IFN-γ positively correlates with Psoriasis
5.3
Lactobacillus plantarum DR7 suppresses IFN-γ
5.1
Curcumin inhibits IFN-γ
5.0
Major depressive disorder increases IFN-γ
5.0
IFN-γ reduces Serotonin
5.0
IFN-γ increases Indoleamine 2,3-Dioxygenase
5.0
Aspirin decreases IFN-γ
3.5
IL-18 activates IFN-γ
(BioMindmap Proof Quality is Acceptable.)
3.5
IFN-γ is Type II IFN
(BioMindmap Proof Quality is Acceptable.)
3.2
Th1 affects IFN-γ
(BioMindmap Proof Quality is Acceptable.)
3.2
NK T cell produces IFN-γ
(BioMindmap Proof Quality is Acceptable.)
3.2
NK cell produces IFN-γ
(BioMindmap Proof Quality is Acceptable.)
3.2
Apigenin decreases IFN-γ
(BioMindmap Proof Quality is Acceptable.)
3.1
Lactobacillus plantarum DR7 reduces IFN-γ
(BioMindmap Proof Quality is Acceptable.)
2.8
Estradiol decreases IFN-γ
(BioMindmap Proof Quality is Acceptable.)
2.6
Psoriasis positively correlates with IFN-γ
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2.4
Melatonin decreases IFN-γ
(BioMindmap Proof Quality is Low.)
2.4
Hashimoto Thyroiditis positively correlates with IFN-γ
(BioMindmap Proof Quality is Low.)
2.2
L. reuteri DSM 17938 decreases IFN-γ
(BioMindmap Proof Quality is Low.)
2.2
Bromelain decreases IFN-γ
(BioMindmap Proof Quality is Low.)
2.2
EGCG decreases IFN-γ
(BioMindmap Proof Quality is Low.)
2.2
L. casei decreases IFN-γ
(BioMindmap Proof Quality is Low.)
2.2
Berberine suppresses IFN-γ
(BioMindmap Proof Quality is Low.)
2.0
IFN-γ inhibits Treg cells
(BioMindmap Proof Quality is Low.)
1.9
L. reuteri ATCC PTA 4659 decreases IFN-γ
(BioMindmap Proof Quality is Low.)
1.9
L. reuteri ATCC PTA 5289 decreases IFN-γ
(BioMindmap Proof Quality is Low.)
1.9
L. reuteri ATCC PTA 6472 decreases IFN-γ
(BioMindmap Proof Quality is Low.)
-0.5
Perhaps, Fisetin decreases expression of IFN-γ
(BioMindmap Proof Quality is Negative.)

Evidence Sources

Biolinks for IFN-γ are extracted by users from 28 related publications.

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