Low Density Lipoprotein
LDL
marker
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«Low-density lipoprotein (LDL) is one of the five major groups of lipoprotein which transport all fat molecules around the body in the extracellular water.[1] These groups, from least dense, compared to surrounding water (largest particles) to most dense (smallest particles), are chylomicrons (aka ULDL by the overall density naming convention), very low-density lipoprotein (VLDL), intermediate-density lipoprotein (IDL), low-density lipoprotein and high-density lipoprotein (HDL). LDL delivers fat molecules to the cell and can drive the progression of atherosclerosis if they become oxidized within the walls of arteries.» (wikipedia)
Summary on LDL
Bolder font means better proofs.
Alt+click opens node.
Lowering of LDL
Pathways of LDL
LDL Biolinks
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-1.2Perhaps, Fructose Diet does not affect LDL(BioMindmap Proof Quality is Negative.) (BioMindmap had flagged this statement.)
Evidence Sources
Biolinks for LDL are extracted by users from 82 related publications.-
2000Meta-Analysis
- Organism: Humans
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2000Cohort
- Organism: Humans
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2004RCT
- Organism: Humans
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2005Cohort
- Organism: Humans
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2007RCT
- Organism: Humans
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2008Cohort
- Organism: Humans
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2008RCT
- Organism: Humans
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2009
- Organism: Humans
- Minor Magnitude of Effect.
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2010RCT
- Organism: Humans
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2011RCT
- Organism: Humans
- Notable Magnitude of Effect.
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2011RCT
- Organism: Humans
- Minor Magnitude of Effect.
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2012RCT
- Organism: Humans
- Minor Magnitude of Effect.
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1990RCT
- Organism: Humans
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2013RCT
- Organism: Humans
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2013Meta-Analysis
- Organism: Humans
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2015RCT
- Organism: Humans
- Minor Magnitude of Effect.
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2018RCT
- Organism: Humans
- Minor Magnitude of Effect.
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2018RCT
- Organism: Humans
- Minor Magnitude of Effect.
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2019RCT
- Organism: Humans
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1995RCT
- Organism: Humans
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1994Meta-Analysis
- Organism: Humans
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1993RCT
- Dose: 600 mg/d
- Organism: Humans
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1993Meta-Analysis
- Organism: Humans
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1996RCT
- Organism: Humans
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1997RCT
- Organism: Humans
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2001Systematic Review
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2020Cohort
- Organism: Humans — Not Healthy
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2008RCT
- Organism: Humans
- Notable Magnitude of Effect.
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2009Publications Review
- Organism: Humans
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2012RCT
- Dose: Each capsule contained 500 mg of RG, including 10 mg of ginsenosides. The RG group took two capsules three times a day (RG 1 g x 3) for 12 weeks.
- Organism: Females — Postmenopausal
- Notable Magnitude of Effect.
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2012Meta-Analysis
- Organism: Humans
- Notable Magnitude of Effect.
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2018RCT
- Condition: in older men with low testosterone
- Organism: Humans
- Minor Magnitude of Effect.
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2018Meta-Analysis
- Organism: Humans
- Notable Magnitude of Effect.
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2018Cohort
- Organism: Humans
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2018Meta-Analysis
- Organism: Humans
- Strong Magnitude of Effect.
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2018Systematic Review
- Organism: Humans
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2018Meta-Analysis
- Organism: Humans
- Notable Magnitude of Effect.
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2018Meta-Analysis
- Organism: Humans
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2019Cohort
- Organism: Humans
- Strong Magnitude of Effect.
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2019Meta-Analysis
- Organism: Humans
- Notable Magnitude of Effect.
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2019Meta-Analysis
- Dose: 4 g/d of betaine
- Organism: Humans
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- Organism: Humans — Not Healthy
- Minor Magnitude of Effect.
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2007Publications Review
- Organism: Humans
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2011
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2012
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2014
- Dose: The subjects participated in progressive aerobic training on treadmill 3 times a week (20 min/session (60% maximum heart rate) to 60 min (75% maximum heart rate).
- Organism: Humans — Sedentary
- Minor Magnitude of Effect.
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2017
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2017
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2018
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2018
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2017RCT
- Organism: Humans — Not Healthy
- Notable Magnitude of Effect.
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2008Rodents
- Organism: Mouse / Rat (Rodents)
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2018Meta-Analysis
- Organism: Humans
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2019RCT
- Dose: 80 mg/day
- Organism: Humans
- Minor Magnitude of Effect.
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2008
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2010
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2011
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2012Meta-Analysis
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2012Systematic Review
- Condition: type-2 diabetes
- Organism: Humans
- Notable Magnitude of Effect.
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2013
- Minor Magnitude of Effect.
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- From this research we know that
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-1.2Perhaps, Fructose Diet does not affect LDL(BioMindmap Proof Quality is Negative.) (BioMindmap had flagged this statement.)
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2013
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2015Systematic Review
- Organism: Humans
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2015Systematic Review
- Organism: Humans
- Notable Magnitude of Effect.
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2016
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2017Meta-Analysis
- Organism: Humans
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2017Meta-Analysis
- Organism: Humans
- Minor Magnitude of Effect.
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2017
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2017Meta-Analysis
- Organism: Humans
- Strong Magnitude of Effect.
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2017Meta-Analysis
- Organism: Humans
- Minor Magnitude of Effect.
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2017
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2018RCT
- Organism: Humans — Healthy
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2018
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2018
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2018
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2019
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2019Systematic Review
- Organism: Humans
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2019RCT
- Organism: Humans
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2020Meta-Analysis
- Organism: Humans
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2020Meta-Analysis
- Organism: Humans — Not Healthy
- Notable Magnitude of Effect.
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2019Systematic Review
- Condition: type 2 diabetic patients
- Organism: Humans
- Notable Magnitude of Effect.
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This screen hints what BioMindmap can do with medical objects
- See 55 Biolinks that connect LDL with other objects
- Group Biolinks by type — promoters and inhibitors separately
- Summarize how other objects relate to LDL
- There are 82 Evidences supporting 55 LDL Biolinks
- See
Guide for Good Sources list of respected domains.
The ValidityScore shows the quality of evidences, with max 9.9.
- LDL Mindmap — near connections
- Mindmap with ValidityScore 5.0 — near connections
- Mindmap of LDL. and Subnodes: .
- Find Path to another object.
- Build Custom Map
- Instream into nodes that connect into LDL.
- Outstream from nodes that go out from LDL.
- Promoters of LDL
- Add biolink i.e. «X increases LDL». Intuitively easy.
- Power-start: watch the Intro Video and Guide in Help Center
- Users improve Reputation by getting experienced and validated.
- Ask Telegram Bot to get quick Summary on any object.