Inhibin B

«Activin and inhibin are two closely related proteincomplexes that have almost directly opposite biological effects. Identified in 1986,[1][2]activin enhances FSHbiosynthesis and secretion, and participates in the regulation of the menstrual cycle. Many other functions have been found to be exerted by activin, including roles in cell proliferation, differentiation, apoptosis,[3]metabolism, homeostasis, immune response, wound repair,[4] and endocrine function. Conversely, inhibin downregulates FSH synthesis and inhibits FSH secretion.[5] The existence of inhibin was hypothesized as early as 1916; however, it was not demonstrated to exist until Neena Schwartz and Cornelia Channing's work in the mid 1970s, after which both proteins were molecularly characterized ten years later.[6]» (wikipedia)

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Pathways of Inhibin B

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