Phenylalanine hydroxylase

«Phenylalanine hydroxylase (PAH) (EC1.14.16.1) is an enzyme that catalyzes the hydroxylation of the aromatic side-chain of phenylalanine to generate tyrosine. PAH is one of three members of the biopterin-dependent aromatic amino acid hydroxylases, a class of monooxygenase that uses tetrahydrobiopterin (BH4, a pteridine cofactor) and a non-heme iron for catalysis. During the reaction, molecular oxygen is heterolytically cleaved with sequential incorporation of one oxygen atom into BH4 and phenylalanine substrate.[5]

  • Has Subnodes:

Pathways of Phenylalanine hydroxylase

Textual paths of Biolinks with Validity Score > 3.0
Uses in-app credits Help
This tool shows paths like: A B C Phenylalanine hydroxylase


Visualisation of logical biolinks between drugs, supplements, symptoms etc..
Generic SubmitterPRO ranked added it 2 years ago on Mar 15, 2020