«Helicobacter pylori, previously known as Campylobacter pylori, is a Gram-negative, helically-shaped, microaerophilicbacterium usually found in the stomach. Its helical shape (from which the genus name, helicobacter, derives) is thought to have evolved in order to penetrate the mucoid lining of the stomach and thereby establish infection. The bacterium was first identified in 1982 by Australian doctors Barry Marshall and Robin Warren, who found that it was present in a person with chronic gastritis and gastric ulcer, conditions not previously believed to have a microbial cause.H. pylori has also been linked to the development of duodenal ulcers, polyps, i. e. benign growths, in the small intestine, large intestine, and rectum, and malignancies of the stomach's secretory glands (termed stomach adenocarcinoma), of the mucosa-associated lymphoid tissue in the stomach, esophagus, colon, rectum, or tissues around the eye (termed extranodal marginal zone B-cell lymphoma of the cited organ), and of lymphoid tissue in the stomach (termed diffuse large B-cell lymphoma).
Many investigators have proposed causal associations between H. pylori and a wide range of other diseases (e.g. idiopathic thrombocytopenic purpura, iron deficiency anemia, atherosclerosis, Alzheimer's disease,multiple sclerosis, coronary artery disease, periodontitis,Parkinson's disease, Guillain-Barre syndrome, rosacea, psoriasis, chronic urticaria, spot baldness, various autoimmune skin diseases, Schoenlein-Henoch purpura, low blood levels of vitamin B12, autoimmune neutropenia, the antiphospholipid syndrome, plasma cell dyscrasias, central serous chorioretinitis, open angle glaucoma, blepharitis, diabetes mellitus, the metabolic syndrome, various types of allergies, non-alcoholic fatty liver disease, non-alcoholic steatohepatitis, hepatic fibrosis, and liver cancer). The bacterial infection has also been proposed to have protective effects for its hosts against infections by other pathogens, asthma, obesity,celiac disease, inflammatory bowel disease,rhinitis, atopic dermatitis,gastroesophageal reflux disease, and esophageal cancer. However, these deleterious and protective effects have frequently been based on correlative rather than direct relationship studies and have often been contradicted by other studies that show either the opposite or no effect on the cited disease. Consequently, many of these relationships are currently regarded as questionable and in need of more definitive studes. They are not considered further here.» (wikipedia)
Do something with Helicobacter pylori, already
This screen hints what BioMindmap can do with medical objects
- See 14 Biolinks that connect Helicobacter pylori
- Group Biolinks by type — promoters and inhibitors separately
- Summarize how other objects relate to Helicobacter pylori
- There are 9 Evidences supporting 14 Helicobacter pylori Biolinks
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The ValidityScore showsthe quality of evidences, with max 9.9.
- Helicobacter pylori Mindmap — near connections
- Mindmap with ValidityScore 5.0 — near connections
- Mindmap of Helicobacter pylori. and Subnodes: .
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