Inducible Nitric Oxide Synthase
«Nitric oxide synthases (EC126.96.36.199) (NOSs) are a family of enzymes catalyzing the production of nitric oxide (NO) from L-arginine. NO is an important cellular signaling molecule. It helps modulate vascular tone, insulin secretion, airway tone, and peristalsis, and is involved in angiogenesis and neural development. It may function as a retrograde neurotransmitter. Nitric oxide is mediated in mammals by the calcium-calmodulin controlled isoenzymes eNOS (endothelial NOS) and nNOS (neuronal NOS). The inducible isoform, iNOS, involved in immune response, binds calmodulin at physiologically relevant concentration, and produces NO as an immune defense mechanism, as NO is a free radical with an unpaired electron. It is the proximate cause of septic shock and may function in autoimmune disease.
NOS catalyzes the reaction:» (wikipedia)
Do something with iNOS, already
This screen hints what BioMindmap can do with medical objects
- See 10 Biolinks that connect iNOS with other objects
- Group Biolinks by type — promoters and inhibitors separately
- Summarize how other objects relate to iNOS
- There are 16 Evidences supporting 10 iNOS Biolinks
Guide for Good Sources list of respected domains.
The ValidityScore showsthe quality of evidences, with max 9.9.
- iNOS Mindmap — near connections
- Mindmap with ValidityScore 5.0 — near connections
- Mindmap of INOS. and Subnodes: .
- Find Path to another object.
- Build Custom Map
- What type is iNOS? Edit type Is it food or drug?
- Add biolink i.e. «X increases iNOS». Intuitively easy.
- Power-start: watch the Intro Video and Guide in Help Center
- Users improve Reputation by getting experienced and validated.
- Ask Telegram Bot to get quick Summary on any object.