Follicle-Stimulating Hormone
FSH
hormone
Favourite
Track
My Medkit
My Symptoms
My Goals
Favourite
Track
My Medkit
My Symptoms
My Goals
Follicle-stimulating hormone (FSH) is a gonadotropin, a glycoprotein polypeptide hormone. FSH is synthesized and secreted by the gonadotropic cell of the anterior pituitary gland,[1] and regulates the development, growth, pubertal maturation, and reproductive processes of the body. FSH and luteinizing hormone (LH) work together in the reproductive system.
<<<<< Text is merged from different submissions.
Summary on FSH
Follicle-Stimulating Hormone is
a
hormone.
Here is an overview of its
34 biolinks
with
acceptable
average validity.
Bolder font means better proofs.
Alt+click opens node.
↑ Increases:
Aromatase, Testicular volume
↑ May increase:
IGF-2
↑ Causes:
Body fat, Bone mass, Reproduction, Sertoli cells
→ Increased by:
Adenosine Receptor, Ageing, Bulbine natalensis, FSHR, GnRH, GnRH, Inhibin B, Kisspeptin, Naltrexone + Neurokinin b, Pituitary gland, Taurine
→ Improved by:
Mucuna Pruriens
↘ Decreased by:
Ashwagandha, Ghrelin, GnIH, Inhibin B, Metformin
↘ May be decreased by:
Melatonin
? Affects:
AMH, Body fat, Testicular volume
? Affected by:
Naltrexone
? Negative correlation:
Diabetes Type 2, MPV, Leptin, Obesity
× Is not affected by:
NKB
Pathways of FSH
Textual paths of Biolinks with
Validity Score > 3.0
This tool shows paths like:
A B C FSH
Add Biolink
FSH Biolinks
-
-0.8Perhaps, Leptin negatively correlates with FSH(BioMindmap Proof Quality is Negative.) (BioMindmap had flagged this statement.)
Evidence Sources
Biolinks for FSH are extracted by users from 37 related publications.
Users read a research at the PubMed. They understand a relation between two objects.
To organise this new finding, they add it as a new piece of information — a Biolink — a proven logical relation between objects, drugs or symptoms etc.
Any user can propose new knowledge which will be reviewed.
Proofs for biolinks of current node (FSH) are listed here. Abstracts are hidden.
-
2008RCT
- Organism: Humans
- Notable Magnitude of Effect.
-
-
2008RCT
- Organism: Humans
- Notable Magnitude of Effect.
-
-
2009RCT
- Organism: Humans
-
-
2009Cohort
- Organism: Humans
-
-
2011RCT
- Organism: Humans
- Notable Magnitude of Effect.
-
-
2013RCT
- Organism: Humans
-
-
2013RCT
- Organism: Humans
-
-
2015RCT
- Organism: Humans
-
-
2019RCT
- Organism: Humans
-
-
2019RCT
- Organism: Humans
-
-
2012Non Random CT
- Dose: pharmacological dose of ghrelin was injected (50 μg) or placebo
- Condition: six healthy women (age, 25.5 ± 2.9 yr)
- Organism: Females
- Notable Magnitude of Effect.
-
- Organism: Humans
-
2001Publications Review
- Organism: Humans
- Notable Magnitude of Effect.
-
-
2004Rodents
- Organism: Mouse / Rat (Rodents)
- Notable Magnitude of Effect.
-
-
2005RCT
- Organism: Males
- Notable Magnitude of Effect.
-
-
2007Publications Review
- Organism: Humans
- Notable Magnitude of Effect.
-
-
2010Rodents
- Dose: The effects of administration of aqueous extract of Bulbine natalensis stem at 25, 50 and 100 mg/kg body weight on the anabolizing and androgenic parameters
- Organism: Mouse / Rat (Rodents)
- Strong Magnitude of Effect.
-
-
2012RCT
- Condition: ewes (sheeps)
- Organism: Mammals
-
-
2013Publications Review
- Organism: Humans
- Strong Magnitude of Effect.
-
-
2015Cohort
- Organism: Humans
- Notable Magnitude of Effect.
-
-
2017Publications Review
- Organism: Mouse / Rat (Rodents)
- Notable Magnitude of Effect.
-
-
2017Rodents
- Organism: Mouse / Rat (Rodents)
- Strong Magnitude of Effect.
-
-
2018Publications Review
- Organism: Mouse / Rat (Rodents)
- Notable Magnitude of Effect.
-
-
1984Rodents
- Dose: The daily dose of 100 ng melatonin in saline was chosen because it was shown to maximally inhibit the different parameters studied
- Organism: Mouse / Rat (Rodents)
- Strong Magnitude of Effect.
-
-
1987Human Cells
- Organism: In vitro
- Notable Magnitude of Effect.
-
-
2013Human Cells
- Dose: All experiments used the KGN human granulosa-like tumor cell line. Cells were cultured overnight at 3 × 105 cells per well in DMEM-F12 (Life Technologies) plus 1% fetal calf serum before addition of medium containing aromatase substrate testosterone (5 × 10−7M) and 10−7M metformin (16 ng/mL); FSH at 1, 5, and 10 ng/mL with or without metformin; or forskolin (Fsk) at 10μM and 25μM with or without metformin (all drugs from Sigma-Aldrich Co Ltd except hFSH from Endocrine Services).
- Organism: In vitro
- Strong Magnitude of Effect.
-
-
2014Cohort
- Condition: healthy, regularly menstruating, premenopausal women
- Organism: Females — Premenopausal
-
- From this research we know that
-
-0.8Perhaps, Leptin negatively correlates with FSH(BioMindmap Proof Quality is Negative.) (BioMindmap had flagged this statement.)
-
2016Cohort
- Condition: postmenopausal women older than 55 years
- Organism: Females — Premenopausal
-
-
2016Cohort
- Organism: Humans
- Notable Magnitude of Effect.
-
-
2018Publications Review
- Organism: Humans
-
-
2019Publications Review
- Organism: Humans
- Notable Magnitude of Effect.
-
-
2019Publications Review
- Organism: Humans
- Notable Magnitude of Effect.
-
-
2019Systematic Review
- Organism: Humans
-
-
2001Systematic Review
- Organism: Humans
- Notable Magnitude of Effect.
-
-
2015RCT
- Organism: Humans — Not Healthy
-
-
2018
- Organism: Humans
-
-
2019Systematic Review
- Organism: Humans
- Notable Magnitude of Effect.
-
See extended map
Login and get extended access to our features that are calculation-heavy.
Map FSH to ...
NB! This is beta feature, which sometimes hangs. We are working on optimising it.
Do something with FSH
Lists what BioMindmap can do with its medical objects for demo purposes.
Biolink is a statement and objects connection.
- See 34 Biolinks that connect FSH with other objects
- Group Biolinks by type — promoters and inhibitors separately
- Summarize how other objects relate to FSH
Biolinks should be proven by researches.
- There are 37 Evidences supporting 34 FSH Biolinks
- See
Guide for Good Sources list of respected domains.
The ValidityScore shows the quality of evidences, with max 9.9.
Textual Paths like
A
→
B
→
C
→
FSH. can be generated from biolinks.
Visualise biolinks!
- FSH Mindmap — near connections
- Mindmap with ValidityScore 5.0 — near connections
- Mindmap of FSH. and Subnodes: .
- Find Path to another object.
- Build Custom Map
FSH has 22 incoming and 12 outgoing biolinks:
- Instream into nodes that connect into FSH.
- Outstream from nodes that go out from FSH.
- Promoters of FSH
When you read PubMed research organise your findings here.
- Add biolink i.e. «X increases FSH». Intuitively easy.
Become better
- Power-start: watch the Intro Video and Guide in Help Center
- Users improve Reputation by getting experienced and validated.
Other options
- Ask Telegram Bot to get quick Summary on any object.
BioMindmap is made with Love and Science to be intuitively clear.