Tumor Suppressor P53 P53 protein

«Tumor protein p53, also known as p53, cellular tumor antigen p53 (UniProt name), the Guardian of the Genome,[5] phosphoprotein p53, tumor suppressor p53, antigen NY-CO-13, or transformation-related protein 53 (TRP53), is any isoform of a protein encoded by homologous genes in various organisms, such as TP53 (humans) and Trp53 (mice). This homolog (originally thought to be, and often spoken of as, a single protein) is crucial in multicellular organisms, where it prevents cancer formation, and thus functions as a tumor suppressor. As such, p53 has been described as "the guardian of the genome" because of its role in conserving stability by preventing genome mutation. Hence TP53. is classified as a tumor suppressor gene.» (wikipedia)

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