Canagliflozin editSet type / Edit


«Canagliflozin, sold under the brand name Invokana among others, is a medication used to treat type 2 diabetes.[1] It is less preferred than metformin.[2] It is used together with exercise and diet.[1] It is not recommended in type 1 diabetes.[1] It is taken by mouth.[1]

Common side effects include vaginal yeast infections, nausea, constipation, and urinary tract infections.[1] Serious side effects may include low blood sugar, Fournier's gangrene, leg amputation, kidney problems, high blood potassium, and low blood pressure.[1]Diabetic ketoacidosis may occur despite nearly normal blood sugar levels.[1] Use in pregnancy and breastfeeding is not recommended.[3] Canagliflozin is a sodium-glucose cotransporter 2 (SGLT2) inhibitor.[1] It works by increasing the amount of glucose lost in the urine.[1]

Canagliflozin was approved for medical use in the United States in 2013.[1] A month's supply in the United Kingdom costs the NHS about £39.20 as of 2019.[2] In the United States the wholesale cost of this amount is about US$475.20.[4] In 2016 it was the 194th most prescribed medication in the United States with more than 3 million prescriptions.[5]» (wikipedia)


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Modified: 1 month ago on Jul 7, 2019
personMoreVitaminov 16 lvl added it 2 months ago on Jun 18, 2019.