Imatinib Set type / Edit

«Imatinib, sold under the brand names Gleevec among others, is a medication used to treat cancer.[1] Specifically, it is used for chronic myelogenous leukemia (CML) and acute lymphocytic leukemia (ALL) that are Philadelphia chromosome-positive (Ph+), certain types of gastrointestinal stromal tumors (GIST), hypereosinophilic syndrome (HES), chronic eosinophilic leukemia (CEL), systemic mastocytosis, and myelodysplastic syndrome.[1] It is taken by mouth.[1]

Common side effects include vomiting, diarrhea, muscle pain, headache, and rash.[1] Severe side effects may include fluid retention, gastrointestinal bleeding, bone marrow suppression, liver problems, and heart failure.[1] Use during pregnancy may result in harm to the baby.[1] Imatinib works by stopping the Bcr-Abl tyrosine-kinase.[1] This can slow growth or result in programmed cell death of certain types of cancer cell.[1]

Imatinib was approved for medical use in the United States in 2001.[1] It is on the World Health Organization's List of Essential Medicines, the most effective and safe medicines needed in a health system.[2] The wholesale cost in the developing world is about 1,386.49 to 19,162.50 USD a year.[3] In the United States a typical dose for a year has a wholesale cost of $84,408.78,[4] while in the United Kingdom the NHS was paying about £20,980 ($27973) in 2016.[5] A generic version became available in the UK as of 2017.[6]» (wikipedia)

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Modified 6 months ago on Jul 7, 2019
MoreVitaminovPRO ranked added it 7 months ago on Jun 18, 2019