«Ketosis is a metabolic state in which some of the body's energy supply comes from ketone bodies in the blood, in contrast to a state of glycolysis in which blood glucose provides energy. Generally, ketosis occurs when the liver is metabolizing fatty acids or ethanol at a high rate in the absence of glucose and converting the product acetyl-CoA into ketone bodies. The first ketone body to be produced is acetoacetate, followed by enzymatic reduction by beta-hydroxybutyrate dehydrogenase to beta-hydroxybutyrate with NADH and a proton as a cofactor, or loss of a carbon dioxide molecule to form acetone. As the liver itself lacks the metabolic machinery required to utilize them, the product ketone bodies are entirely released into the blood for use by the rest of the body.

  • Subnodes

Modified: 3 months ago on Jul 7, 2019
personAlex Inside 23 lvl added it 4 months ago on Jun 15, 2019.