Alanine Transaminase
ALT
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«Alanine transaminase (ALT) is a transaminaseenzyme (EC2.6.1.2). It is also called alanine aminotransferase (ALAT) and was formerly called serum glutamate-pyruvate transaminase (SGPT) or serum glutamic-pyruvic transaminase (SGPT) and was first characterized in the mid-1950s by Arthur Karmen and colleagues.[1] ALT is found in plasma and in various body tissues, but is most common in the liver. It catalyzes the two parts of the alanine cycle. Serum ALT level, serum AST (aspartate transaminase) level, and their ratio (AST/ALT ratio) are commonly measured clinically as biomarkers for liver health. The tests are part of blood panels.» (wikipedia)
Summary on ALT
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Pathways of ALT
ALT Biolinks
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-2.1Perhaps, Artichoke may decrease ALT(BioMindmap Proof Quality is Negative.) (BioMindmap had flagged this statement.)
Evidence Sources
Biolinks for ALT are extracted by users from 14 related publications.-
2008Non Random CT
- Dose: 2 g taurine three times per day for 3 months
- Organism: Humans
- Notable Magnitude of Effect.
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2010RCT
- Dose: en DMD patients age 12.8 +/- 0.98 yr, were treated with melatonin (60 mg at 21:00 hr plus 10 mg at 09:00 hr)
- Organism: Humans
- Strong Magnitude of Effect.
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2016Cohort
- Organism: Humans
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2019Rodents
- Organism: Mouse / Rat (Rodents)
- Notable Magnitude of Effect.
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2020RCT
- Organism: Females
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2021Rodents
- Organism: Mouse / Rat (Rodents)
- Strong Magnitude of Effect.
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- Condition: if high
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2017
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2019RCT
- Dose: 80 mg/day
- Organism: Humans
- Minor Magnitude of Effect.
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2011Non Random CT
- Condition: in healthy obese men
- Organism: Humans — Healthy
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2018
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- From this research we know that
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-2.1Perhaps, Artichoke may decrease ALT(BioMindmap Proof Quality is Negative.) (BioMindmap had flagged this statement.)
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2020Meta-Analysis
- Organism: Humans — Not Healthy
- Notable Magnitude of Effect.
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2020RCT
- Organism: Humans — Not Healthy
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- See 14 Biolinks that connect ALT with other objects
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- Summarize how other objects relate to ALT
- There are 14 Evidences supporting 14 ALT Biolinks
- See
Guide for Good Sources list of respected domains.
The ValidityScore shows the quality of evidences, with max 9.9.
- ALT Mindmap — near connections
- Mindmap with ValidityScore 5.0 — near connections
- Mindmap of ALT. and Subnodes: .
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- Instream into nodes that connect into ALT.
- Outstream from nodes that go out from ALT.
- Promoters of ALT
- Add biolink i.e. «X increases ALT». Intuitively easy.
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