Gilbert's syndrome and the risk of death: a population-based cohort study.
RESULTS: During the 350 000 PYs of follow up across the Gilbert's and comparison cohorts, there were 1174 deaths. Mortalityrates were 24/10 000 PYs in the Gilbert's cohort versus 50/10 000 PYs in the comparison cohort. Mortalityrates were around half in patients with Gilbert's syndrome after accounting for sociodemographics and general health indicators (adjusted mortality rate ratio: 0.5 [95% confidence interval; 0.4-0.7; P < 0.001]).
CONCLUSIONS: Mortalityrates observed for people with Gilbert's syndrome in the general population are almost half those of people without evidence of Gilbert's syndrome.