2.2
ValidityScore
Valid or Invalid?
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2016Rodents
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Griffin N, Guo S, Hu X, Shan F, Wang X, Yi Z, Zhang X
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«Now in our current study we have found that the function of LDN on macrophages is present as evidenced by following fact: (1) LDN could significantly up-regulate the expression of CD64 and down-regulate the expression of CD206, which means that macrophages under influence of LDN have shifted into activated M1type;»
- Organism: Mouse / Rat (Rodents)
- Notable Magnitude of Effect.
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#Alcoholism / drug therapy*, Analgesics, Animals, Cells, Cultured, Fengping Shan, Humans, IgG / metabolism, Immunologic Factors / pharmacology*, Inbred BALB C, Interleukin-12 / metabolism, Lymphocyte Activation / drug effects, MEDLINE, Macrophage Activation / drug effects, Macrophages / drug effects*, Macrophages / immunology, Mice, NCBI, NIH, NLM, Naltrexone / pharmacology*, National Center for Biotechnology Information, National Institutes of Health, National Library of Medicine, Nitric Oxide / metabolism, Opioid, Opioid / adverse effects, PubMed Abstract, Receptors, Shengnan Guo, Substance-Related Disorders / drug therapy*, Tumor Necrosis Factor-alpha / metabolism, Zhe Yi, delta / antagonists &, doi:10.1016/j.intimp.2016.08.015, inhibitors, pmid:27561742more...
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added it
1 year ago
on May 14, 2021
ranked