High Protein Diet
may decrease
HbA1C
(BioMindmap Proof Quality is Acceptable.)
High Protein Diet
may decrease
HbA1C
(BioMindmap Proof Quality is Acceptable.)
3.8
ValidityScore
Valid or Invalid?
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2013Meta-Analysis
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Dong JY, Qin LQ, Wang PY, Zhang ZL
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«Abstract: High-protein diet are popular for weight management, but the health effects of such diet in diabetic persons are inconclusive. The aim of the present meta-analysis was to examine the effects of high-protein diet on body weight and metabolic risk factors in patients with type 2 diabetes. We searched the PubMed and Cochrane Library databases for relevant randomised trials up to August 2012. Either a fixed- or a random-effects model was used to combine the net changes in each outcome from baseline to the end of the intervention. Overall, nine trials including a total of 418 diabetic patients met our inclusion criteria. The study duration ranged from 4 to 24 weeks. The actual intake of dietary protein ranged from 25 to 32% of total energy in the intervention groups and from 15 to 20% in the control groups. Compared with the control diet, high-protein diet resulted in more weight loss (pooled mean difference: 22.08, 95% CI 23.25, 20.90 kg). High-protein diet significantly decreased glycated Hb A1C (HbA1C) levels by 0.52 (95% CI 20.90, 20.14) %, but did not affect the fasting blood glucose levels. There were no differences in lipid profiles. The pooled net changes in systolic and diastolic blood pressure were 23.13 (95% CI 26.58, 0.32)mmHg and 21.86 (95% CI 24.26, 0.56) mmHg, respectively. However, two studies reported a large influence on weight loss and HbA1C levels, respectively. In summary, high-protein diet (within 6 months) may have some beneficial effects on weight loss, HbA1C levels and blood pressure in patients with type 2 diabetes. However, further investigations are still required to draw a conclusion.»
- Organism: Humans
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#Blood Glucose / drug effects*, Blood Pressure / drug effects*, Body Weight / drug effects*, Diabetes Mellitus, Dietary Proteins / administration &, Dietary Proteins / pharmacology*, Humans, Jia-Yi Dong, Li-Qiang Qin, Lipids / blood*, MEDLINE, Meta-Analysis, NCBI, NIH, NLM, National Center for Biotechnology Information, National Institutes of Health, National Library of Medicine, Non-U.S. Gov', PubMed Abstract, Research Support, Review, Type 2 / metabolism*, Zeng-Li Zhang, doi:10.1017/S0007114513002055, dosage, pmid:23829939, t
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added it
5 months ago
on Sep 14, 2020
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