Panax Ginseng
decreases
TNF-α
Panax Ginseng
decreases
TNF-α
4.8
ValidityScore
Valid or Invalid?
Of eight included trials, three studies reported the effect of ginseng supplementation on TNF‐α serum level, which included 156 participants (80 cases and 76 controls). We found that ginseng supplementation decreased TNF‐α serum level significantly (MD: −2.471 pg/ml, 95% CI [−2.904, −2.039], p < .001).
-
2019Meta-Analysis
-
Afshari M, Arab A, Ferguson AJR, Ghaedi E, Hadi A, Kord-Varkaneh H, Mohammadi H -
«The present meta‐analysis has shown that Panax Ginseng supplementation resulted in significant, positive effects on selected inflammatory markers. On the basis of these data, we conclude that ginseng supplementation may significantly lower IL‐6 and TNF‐α but not significantly lower CRP. However, these findings need further validation. Furthermore, sensitivity analysis showed that analysis without one of the included studies (Jung et al., 2016) indicated a significant effect of ginseng on CRP. Additionally, results for IL‐6 were sensitive for another
study (Hong et al., 2016) resulting in a change to a nonsignificant value
upon removal of the study. Due to sensitive results, future long‐term,
well‐designed, dose‐escalating trials are required to further evaluate
the effect of ginseng on inflammatory biomarkers.» - Organism: Humans
- Notable Magnitude of Effect.
-
#10.1002/ptr.6399, 31161680, Amir Hadi, Biomarkers / blood*, C-Reactive Protein / chemistry*, Dietary Supplements / analysis*, Ehsan Ghaedi, Hamed Mohammadi, Humans, Inflammation / blood, Inflammation / drug therapy*, MEDLINE, Middle Aged, NCBI, NIH, NLM, National Center for Biotechnology Information, National Institutes of Health, National Library of Medicine, Panax / chemistry*, PubMed Abstractmore... -
ranked
added it
2 years ago
on May 24, 2020