Sleep
prevents
Common Cold
(BioMindmap Proof Quality is Acceptable.)
Sleep
prevents
Common Cold
(BioMindmap Proof Quality is Acceptable.)
3.4
ValidityScore
Valid or Invalid?
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2015Non Random CT
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Aric A. Prather, Denise Janicki-Deverts, Martica H. Hall, Sheldon Cohen -
«RESULTS: A total of 164 healthy men and women (age range, 18 to 55 y) volunteered for this study. Wrist actigraphy and sleep diaries assessed sleep duration and sleep continuity over 7 consecutive days. Participants were then quarantined and administered nasal drops containing the rhinovirus, and monitored over 5 days for the development of a clinical cold (defined by infection in the presence of objective signs of illness). Logistic regression analysis revealed that actigraphy- assessed shorter sleep duration was associated with an increased likelihood of development of a clinical cold. Specifically, those sleeping < 5 h (odds ratio [OR] = 4.50, 95% confidence interval [CI], 1.08–18.69) or sleeping between 5 to 6 h (OR = 4.24, 95% CI, 1.08–16.71) were at greater risk of developing the cold compared to those sleeping > 7 h per night; those sleeping 6.01 to 7 h were at no greater risk (OR = 1.66; 95% CI 0.40–6.95). This association was independent of prechallenge antibody levels, demographics, season of the year, body mass index, psychological variables, and health practices. Sleep fragmentation was unrelated to cold susceptibility. Other sleep variables obtained using diary and actigraphy were not strong predictors of cold susceptibility.
CONCLUSIONS: Shorter sleep duration, measured behaviorally using actigraphy prior to viral exposure, was associated with increased susceptibility to the common cold.» - Organism: Humans
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2009Cohort
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Cuneyt M. Alper, Denise Janicki-Deverts, Ronald B. Turner, Sheldon Cohen, William J. Doyle -
«RESULTS: There was a graded association with average sleep duration, with those with <7 hours sleep 2.94 times (CI[95%]=1.18–7.30) more likely to develop a cold than those with ≥ 8 hours. The association with sleep efficiency was also graded with those with < 92% efficiency 5.50 times (CI[95%]=2.08–14.48) more likely to develop a cold than those with efficiencies ≥98%. These relations could not be explained by differences in pre-challenge virus-specific antibody, demographics, season of the year, body mass, socioeconomic status, psychological variables or health practices. Percent of days feeling rested was not associated with colds.
CONCLUSIONS: Poorer sleep efficiency and shorter sleep duration in the weeks preceding an exposure to a rhinovirus were associated with lower resistance to illness.» -
Comments: Participants were 153 healthy men and women volunteers, ages 21–55
- Organism: Humans — Healthy
- Strong Magnitude of Effect.
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ranked
added it
3 years ago
on Mar 30, 2020