Xenon anesthesia
does not affect
Cognition
Xenon anesthesia
does not affect
Cognition
4.5
ValidityScore
Valid or Invalid?
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2018Meta-Analysis
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Chan CC, Gan TJ, Law LS, Lo EA
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«Thirteen RCT compared neurocognitive effects of xenon with other anesthetic agents in surgical patients. While xenon may be associated with improved short-term (< three hours) cognitive outcome, no medium-term (six hours to three months) advantage was observed, and longer-term data are lacking. No differences in biochemical (S-100β, neuron-specific enolase) and neuropsychologic (attentional performance) outcomes were found with xenon compared with other anesthetic drugs. Finally, two studies suggest that brief, intermittent administration of sub-anesthetic doses of xenon to patients during the acute phase of substance withdrawal may improve neurocognitive outcomes.»
- Organism: Humans
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#10.1007/s12630-018-1163-6, 29858987, Anesthesia, Animals, Asphyxia Neonatorum / therapy, Cognition / drug effects, Elaine Ah-Gi Lo, General, Humans, Hypothermia, Induced, Infant, Lawrence Siu-Chun Law, MEDLINE, NCBI, NIH, NLM, National Center for Biotechnology Information, National Institutes of Health, National Library of Medicine, Newborn, Out-of-Hospital Cardiac Arrest / therapy, PubMed Abstract, Substance Withdrawal Syndrome / drug therapy, Tong Joo Gan, Xenon / pharmacology, Xenon / therapeutic use
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added it
1 year ago
on Feb 4, 2020
ranked